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Cluster Headache

  • Writer: Consultant Physician
    Consultant Physician
  • Mar 14, 2023
  • 2 min read

Updated: Sep 29, 2023

Cluster headache is a type of headache disorder characterized by recurrent, severe headaches on one side of the head. These headaches often come in "clusters," meaning that they occur several times a day for several weeks or months and then subside for a period of time before returning.

The pain associated with cluster headaches is often described as intense, sharp, or burning and can be accompanied by other symptoms such as redness or tearing of the eye, runny or congested nose, and sweating on the affected side of the face.

The exact cause of cluster headaches is not fully understood, but some factors that may contribute to the development of these headaches include genetic factors, changes in circadian rhythms, and abnormalities in the hypothalamus, a part of the brain that regulates functions such as sleep, hunger, and thirst.

Cluster headaches are characterized by several specific symptoms that can help differentiate them from other types of headaches. Some common symptoms of cluster headaches include:
  • Severe pain: The pain associated with cluster headaches is usually intense and located on one side of the head, often behind or around the eye.

  • One-sided location: Cluster headaches are almost always felt on one side of the head.

  • Rapid onset: The pain of a cluster headache comes on quickly, often within 5 to 10 minutes.

  • Short duration: While the pain of a cluster headache can be severe, it usually lasts only for 15 minutes to 3 hours.

  • Recurrent attacks: Cluster headaches often occur in clusters, with several attacks happening daily for several weeks to months, followed by a period of remission.

  • Autonomic symptoms: Cluster headaches are often accompanied by other symptoms on the same side of the head as the pain, including redness or tearing of the eye, runny or congested nose, and sweating.

  • Timing: Cluster headaches often occur at the same time each day, often in the early morning or late evening.


Treatment for cluster headaches usually involves a combination of preventive and abortive measures. The specific treatment plan will depend on the frequency and severity of the headaches, as well as the individual patient's needs and preferences.
  • Preventive measures: Medications such as verapamil, lithium, and corticosteroids may be prescribed to prevent the onset of cluster headache attacks. These medications are taken on a daily basis to reduce the frequency and severity of headaches.

  • Abortive measures: In the event of an attack, oxygen therapy or triptans (such as sumatriptan) may be used to stop the headache. Oxygen therapy involves inhaling 100% oxygen through a mask for 15 to 20 minutes, while triptans are taken as a nasal spray or tablet.

  • Invasive procedures: In severe cases, invasive procedures such as nerve blocks or surgical intervention may be recommended. These procedures involve injecting anesthetic agents or other medications directly into the affected nerves or specific areas of the head and neck.


It is important to note that not all patients with cluster headaches will respond to the same treatments, and some may require a combination of treatments to effectively manage their symptoms. If you are experiencing cluster headaches, it is important to consult a healthcare provider for an accurate diagnosis and appropriate treatment plan.

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